My guess is this will become a never ending problem. The reason is we have so much international travel and we are getting more and more strains of different viruses and diseases which quickly spread. This was seen in past century but on a more limited scale. Example the American Indians had no defense against many diseases the Europeans brought with them.
In Los Angeles County we have very large immigrant populations who do not have good hi-gene habits and many refuse to stop doing what they have always done. I see this in the middle eastern small business owners, in my area many of the liquor stores are owned by Syrians, Jordanians, Koreans etc and most do not wear masks, they don't sanitize counters and they smoke a lot of cigarettes, and coughing without covering their mouths is standard protocol. The you have cultures where standing in your face is the way they were raised and their culture operates, where most born and raised in America have what I call the minimum 3 foot rule, we also tend to talk at a certain voice level but in some cultures they are almost yelling as they talk or discuss something and dispensing their viral load into the other persons face.
So you take a melting pot and its a breeding ground for the spread of disease. Unfortunately due to PC our health officials or schools cannot train or teach people good public health practices. So in the end , I expect to see more and more serious pandemics. Plus now we are used to mass panic and a belief by people that politicians can solve all their health problems.
A world wide economic collapse, is when starvation accelerates and the spread of disease and you end up in a situation like third world nations, where hunger and disease is just accepted as a way of life.
Based on past History WW-1 & WW-11 both were beginning during economic depressions. Unfortunately, the Black Swan that may sucker punch us and kill us all is not a disease or pandemic but a Nuclear Attack and a new regime will take over and finish us off because they would not need or want to be feeding millions of Americans. China and Russia have lost millions over the years and they didn't bat an-eye because life simply has no worth in many of these regimes. My expectation is 2021 will be a year that we find out that we are no longer the Big Dog in the cage and our enemy's may take advantage of us all being focused on a disease and its a good opportunity to hit us first. 50 ICBMs and every Major City in America is gone in 45 minutes, YES we would counter attack with our ICBMs but the difference is we don't have the ability to get back on our feet. The Russians and Chinese would simply bury there millions of bodies and get back on their feet.